Surface proteins of streptococcus pyogenes
β-hemolytic streptococci polynucleotides, polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, and antibodies of these polypeptides are described. The polynucleotides,...
View ArticlePurification method
A process for purifying a Streptococcus pyogenes GAS carbohydrate comprising a step of anionic exchange chromatography. The process provides a good yield of GAS carbohydrate. The saccharides of the...
View ArticleImmunogenic and therapeutic compositions for streptococcus pyogenes
Compositions for preventing and/or treating S. pyogenes infection which comprise one or more active agents. The active agents are SLO antigens, nucleic acid molecules encoding the SLO antigens, and/or...
View ArticleNucleic acids and proteins from streptococcus groups a and b
The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding...
View ArticleImmunizing composition for reducing streptococcal infections
An antigenic composition comprises at least one antigen, wherein said at least one antigen comprises at least part of a protein selected from EndoSe of Streptococcus equi subsp. Equi, EndoSz of...
View ArticleAptamers selected against live s. pyogenes cells
The invention is directed to aptamers, methods and kits comprising same for detecting Streptococcus pyogenes. The method of screening a subject for Streptococcus pyogenes involves obtaining a body...
View ArticleDiagnostic and therapeutic methods for rheumatic heart disease based upon...
This invention is in the field of identifying patients having rheumatic heart disease (RHD) associated with Streptococcus pyogenes (Group A Streptococcus; GAS) infection and identifying patients at...
View ArticleImmunogenic compositions for streptococcus pyogenes
The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40,...
View ArticlePseudomonas aeruginosa strain developed for improving fatty acid content, and...
Disclosed are novel Pseudomonas aeruginosa strains capable of producing in high yield and preparation methods thereof. The strains anchor an expression vector carrying either or both of a nucleotide...
View ArticleStreptococcus pyogenes antigens
The present invention discloses isolated nucleic acid molecules encoding a hyperimmune serum reactive antigen or a fragment thereof as well as hyperimmune serum reactive antigens or fragments thereof...
View ArticleNucleic acids and proteins from streptococcus groups a and b
The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding...
View ArticleStreptococcus pyogenes antigens and corresponding dna fragments
The present invention relates to antigens, more particularly antigenS of Streptococcus pyogenes (also called group A Streptococcus (GAS)) bacterial pathogen which are useful as vaccine component for...
View ArticleVaccine composition against streptococcus pyogenes infection
The present invention relates to a vaccine composition against Streptococcus pyogenes infection comprising an amino acid sequence having C-terminal fragment of streptococcal pyrogenic exotoxin B, and...
View ArticleSmall streptococcus pyogenes antigens and their use
The present invention relates to a peptide consisting of one antigen of Streptococcus pyogenes (S. pyogenes) of any of the SEQ ID NOS: 1 to 7 or a functional active variant thereof, optionally further...
View ArticleImmunogenic compositions for streptococcus pyogenes
The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40,...
View ArticleMulticomponent immunogenic composition for the prevention of beta-hemolytic...
A number of β-hemolytic streptococci polynucleotides and polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, are described. Two or more of the polypeptides of the...
View ArticleNovel lactic acid bacteria and compositions containing them against bacterial...
The invention describes a microorganism of the order of lactic acid bacteria or an analogue, fragment, derivative, mutant or combination thereof, wherein the microorganism, or analogue, fragment,...
View ArticleCrispr/cas systems for genomic modification and gene modulation
The invention relates to engineered CRISPR/Cas9 systems for genomic modification and regulation of gene expression in mammalian cells. The specification describes the design and validation of...
View ArticleCompositions and methods directed to crispr/cas genomic engineering systems
The invention relates to engineered CRISPR/Cas9 systems for genomic modification in mammalian cells. The present specification describes the design and testing of a polynucleotide encoding the...
View ArticleEndoglycosidase from streptococcus pyogenes and methods using it
The invention provides an endoglycosidase, referred to as EndoS49 and having the amino acid sequence of SEQ ID NO: 1. EndoS49 was isolated from Streptococcus pyogenes strain NZ131 and is a homolog of...
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